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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1902 1
1907 1
1911 1
1916 4
1923 1
1929 1
1936 1
1940 1
1948 1
1952 1
1953 1
1956 1
1960 1
1961 1
1963 1
1964 1
1965 1
1970 4
1972 2
1973 5
1974 4
1975 21
1976 27
1977 25
1978 15
1979 24
1980 28
1981 30
1982 32
1983 32
1984 46
1985 48
1986 36
1987 50
1988 51
1989 70
1990 64
1991 68
1992 74
1993 80
1994 86
1995 114
1996 108
1997 132
1998 107
1999 126
2000 154
2001 122
2002 128
2003 126
2004 152
2005 191
2006 191
2007 222
2008 252
2009 254
2010 244
2011 307
2012 289
2013 323
2014 346
2015 331
2016 327
2017 393
2018 375
2019 387
2020 430
2021 490
2022 435
2023 453
2024 216

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7,772 results

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Page 1
iDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging.
Renier N, Wu Z, Simon DJ, Yang J, Ariel P, Tessier-Lavigne M. Renier N, et al. Cell. 2014 Nov 6;159(4):896-910. doi: 10.1016/j.cell.2014.10.010. Epub 2014 Oct 30. Cell. 2014. PMID: 25417164 Free article.
We describe a simple, rapid, and inexpensive method, iDISCO, that permits whole-mount immunolabeling with volume imaging of large cleared samples ranging from perinatal mouse embryos to adult organs, such as brains or kidneys. iDISCO is modeled on classical histology techniques, …
We describe a simple, rapid, and inexpensive method, iDISCO, that permits whole-mount immunolabeling with volume imaging of large cleared sa …
Retinal Plasticity.
Strettoi E, Di Marco B, Orsini N, Napoli D. Strettoi E, et al. Int J Mol Sci. 2022 Jan 20;23(3):1138. doi: 10.3390/ijms23031138. Int J Mol Sci. 2022. PMID: 35163059 Free PMC article. Review.
As a part of the CNS, the retina has been repeatedly probed for its possible ability to respond plastically to a variably altered environment or to pathological insults. However, numerous studies support the conclusion that the retina, outside the developmental stage, is e …
As a part of the CNS, the retina has been repeatedly probed for its possible ability to respond plastically to a variably altered env …
Degenerate neuronal systems sustaining cognitive functions.
Noppeney U, Friston KJ, Price CJ. Noppeney U, et al. J Anat. 2004 Dec;205(6):433-42. doi: 10.1111/j.0021-8782.2004.00343.x. J Anat. 2004. PMID: 15610392 Free PMC article. Review.
In degenerate functional neuroanatomy, multiple degenerate neuronal systems might be present in a single brain where they are either co-activated or remain latent during task performance. ...Degeneracy over subjects might have arisen from (ab)normal variation in neu …
In degenerate functional neuroanatomy, multiple degenerate neuronal systems might be present in a single brain where they are …
Optic Atrophy.
Ahmad SS, Kanukollu VM. Ahmad SS, et al. 2022 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2022 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 32644556 Free Books & Documents.
It is this neuro-vascular degeneration which forms the foundation for the development of optic atrophy. ...The degenerated axons also lose the optical property of total internal reflection, leading to the pale optic disc seen in this condition. ...
It is this neuro-vascular degeneration which forms the foundation for the development of optic atrophy. ...The degenerated axo …
Late-onset hereditary ataxias with dementia.
Linares AJ, Fogel BL. Linares AJ, et al. Curr Opin Neurol. 2023 Aug 1;36(4):324-334. doi: 10.1097/WCO.0000000000001170. Epub 2023 Jun 2. Curr Opin Neurol. 2023. PMID: 37382141 Review.
PURPOSE OF REVIEW: Late-onset genetic cerebellar ataxias are clinically heterogenous with variable phenotypes. Several of these conditions are commonly associated with dementia. ...RECENT FINDINGS: Spinocerebellar ataxias often present with variable phenotypes that …
PURPOSE OF REVIEW: Late-onset genetic cerebellar ataxias are clinically heterogenous with variable phenotypes. Several of these condi …
Degenerate sequence-based CRISPR diagnostic for Crimean-Congo hemorrhagic fever virus.
Li H, Bello A, Smith G, Kielich DMS, Strong JE, Pickering BS. Li H, et al. PLoS Negl Trop Dis. 2022 Mar 10;16(3):e0010285. doi: 10.1371/journal.pntd.0010285. eCollection 2022 Mar. PLoS Negl Trop Dis. 2022. PMID: 35271569 Free PMC article.
We test this crRNA design strategy in the context of the Cas13a-based SHERLOCK (specific high-sensitivity enzymatic reporter unlocking) technology for detection of Crimean-Congo hemorrhagic fever virus (CCHFV), a biosafety level 4 pathogen with wide geographic distribution and br …
We test this crRNA design strategy in the context of the Cas13a-based SHERLOCK (specific high-sensitivity enzymatic reporter unlocking) tech …
Variably protease-sensitive prionopathy.
Notari S, Appleby BS, Gambetti P. Notari S, et al. Handb Clin Neurol. 2018;153:175-190. doi: 10.1016/B978-0-444-63945-5.00010-6. Handb Clin Neurol. 2018. PMID: 29887135
Variably protease-sensitive prionopathy (VPSPr), originally identified in 2008, was further characterized and renamed in 2010. ...Distinguishing clinical features include a median 2-year duration and presentation with psychiatric signs, speech/language impairment, or cogni …
Variably protease-sensitive prionopathy (VPSPr), originally identified in 2008, was further characterized and renamed in 2010. ...Dis …
DNA repair in trinucleotide repeat ataxias.
Yau WY, O'Connor E, Sullivan R, Akijian L, Wood NW. Yau WY, et al. FEBS J. 2018 Oct;285(19):3669-3682. doi: 10.1111/febs.14644. Epub 2018 Sep 10. FEBS J. 2018. PMID: 30152109 Free article. Review.
Currently, there is no available treatment to alter the disease trajectory, with devastating consequences for affected individuals. Inter- and Intrafamily phenotypic variability suggest the existence of genetic modifiers, which may become targets amendable to treatment. .. …
Currently, there is no available treatment to alter the disease trajectory, with devastating consequences for affected individuals. Inter- a …
Cerebellar/spinocerebellar syndromes.
Mariotti C, Di Donato S. Mariotti C, et al. Neurol Sci. 2001 Nov;22 Suppl 2:S88-92. doi: 10.1007/s100720100042. Neurol Sci. 2001. PMID: 11794486 Review.
Clinical classification and differential diagnosis are intricate due to the great variability of the phenotypic, pathogenic, neuropathological and genetic aspects of these diseases. ...
Clinical classification and differential diagnosis are intricate due to the great variability of the phenotypic, pathogenic, neuropat …
Clinical electro-oculography.
Alanko HI. Alanko HI. Acta Ophthalmol Suppl. 1984;161:139-48. doi: 10.1111/j.1755-3768.1984.tb06796.x. Acta Ophthalmol Suppl. 1984. PMID: 6328846
EOG is a valuable clinical tool in diagnosis of tapetoretinal degenerations, vitelliform foveal dystrophy including the carriers of this disease, retinal intoxications and in differential diagnosis of choroidal malignant melanomas. ...The main drawback of the present techn …
EOG is a valuable clinical tool in diagnosis of tapetoretinal degenerations, vitelliform foveal dystrophy including the carriers of t …
7,772 results